If you are looking for the best brain supplements to use, chances are that you have come across the word “racetam” quite a few times. But what on earth are they?
In the following guide, we’ll talk about the best racetam powders available out there currently.
Keep scrolling to learn more.
Well, they are a group of cognitive enhancers that can help you to focus, improve your brain health, enhance your memory, and offer anti-anxiety support.
They are synthetically (artificially) made in the sense that they are prepared in the lab. In fact, the oldest known nootropic known is a racetam that was created in the 1960s by Dr. Corneliu E. Giurgea who is widely considered the father of noots.
Now that we have an idea what these drugs really are and what they do, let us get down to business. The following is a comprehensive guide to racetam brain supplements.
Aloracetam is a nootropic drug that belongs to the racetam family. It was created by a French pharmaceutical company known as Sanofi-Aventis as a potential treatment to the Alzheimer’s disease.
Interestingly, the drug has never been marketed and this explains why it is probably the least popular of all the racetam nootropic powders.
This fat-soluble racetam has, however, struggled to gain recognition worldwide and it was at one time discontinued in Japan and Germany.
The drug isn’t approved by the FDA and is categorized as an unscheduled compound. In terms of benefits, it works quite well in supporting brain development at the neuronal level.
On top of that, it is a neuroprotectant meaning that it prevents further damage of brain cells and nerves – effectively boosting long-term potentiation.
When used in combination with other medications, Levetiracetam is an anticonvulsant that treats seizure disorders like epilepsy. Levetiracetam has been confirmed to lessen the number of seizures in adults and children. Details are not yet clear on how it works to inhibit seizures.
Keppra, the medicine used to treat epilepsy contains the active ingredient levetiracetam. The way it works is by calming electrical commotion in the brain.
The brain and nerves are made up of many nerve cells that communicate with each other through electrical signals. Nerve cells in the brain communicate using these electric signals in the brain.
So does levetiracetam have any side effects?
Yes, it does. Some users have reported weakness, unusual tiredness, and drowsiness. These are more prevalent during the first month of taking levetiracetam as the medication infiltrates your body.
However, if the effects get worse or last longer, you should consult with your physician right away.
Seletracetam is derived from the pyrrolidone drug of the racetam family that is fundamentally related to levetiracetam. The racetam was initially developed by the UCB pharmaceutical company as a potentially more powerful and active anticonvulsant drug with the potential to be used as a substitute to Levetiracetam.
However, its development has been put on hold for now.
Generally, the idea behind this drug is to create a system that directly impacts the release of neurotransmitters. Besides that, it helps tone down pressure at the neuronal level thereby stabilizing mental activity.
How does this relate to my brain health? You might be wondering. Well, by toning down the activity of your neurons, Seletracetam helps reduce the occurrence of seizures.
It also protects you against potential neuronal degradation which may lead to a premature loss of memory of other crucial brain functions.
Lastly, you can bank on this nootropic powder to reduce the risk of epilepsy as it tends to reduce the amount of calcium inflow in the brain.
But as we have mentioned, Seletracetam is still under study and is also yet to be approved by the FDA. So, we still need to give the scientists time to understand it so it can be availed either under prescription or over-the-counter.
Brivaracetam is a racetam derived from levetiracetam and is vital in the treatment of partial-onset seizure attacks. Brivaracetam combines with the brain sites where neurotransmitters like dopamine are produced in pretty much the same way levetiracetam does (but 20 times better).
For now, Brivaracetam exits under the brand name Briviact which is a product of the UCB pharmaceutical company.
The product is mainly prescribed to manage partial-onset seizures in kids aged 4 years and above. Its benefits can help protect one from having to reach a stage where they need anti-epileptic medication.
However, this racetam has a number of side effects among them:
Dimiracetam is yet another one of the members of the racetam nootropics family. And in this review, we’d like to confirm that it plays a key role in the management of neuropathic pain.
Besides its antineuropathic pain properties, it plays a major role in the management of cognitive impairment.
But generally, its advanced formula makes it ideal for prescription-based use. For instance, your doctor may recommend it to you if you’re undergoing chemotherapy, facing osteoarthritis or nerve injury. It’s a really good pain management tool that you can always count on.
As you know, there are very few therapeutic choices for calming down neuropathic pain. And in that case, Dimiracetam presents you with the best possible, harmless treatment option.
If you thought you knew each and every member of the racetam family think again – here comes the one and only Rolziracetam.
This is a nootropic drug that is commonly used in the management of cognitive decline in old age. It also can be used to restore normalcy in cognitively impaired human beings.
If you’re always feeling sluggish and struggling to remain focused when undertaking demanding tasks, Rolziracetam might be of help.
However, a lot more studies need to be done to ascertain its benefits and potential long-term implications. So, for now, we’d prefer that you first talk to your doctor prior to using it in any way.
Most of the well-known racetams contain the phenyl group but Piperacetam is different. Instead, it contains piperazine.
So far, research about this nootropic is still at its earliest stages although the outcomes so far have been quite promising. For instance, in this study scientists found out that Piperacetam has benefits that are closely related to those of ampakines (a class of nootropics associated with the enhanced production of neurotransmitters like glutamate).
So far, a compound known as Sunifiram has been developed and is believed to have piracetam-like effects. In fact, scientists in the said study observed that you need a dose of 0.001mg/kg of piperacetam to achieve the same effects as 30 mg/kg of piracetam.
That makes piperacetam 30,000 times more powerful than piracetam (and potentially 30 times more powerful than Noopept).
All we’d say for now is that it’s still early days for this racetam nootropic family member. More studies still need to be done on it.
But should everything fall in the right place, this might just be the supplement that will dethrone Noopept as the best racetam of the century.
Watch this space!
Whew! Quite a long read…but we’re glad that you’ve made it to this end. And we hope that you’ve also been able to meet with a supplement that you’d consider the best racetam nootropic for your situation.
You might also want to read more on this best nootropic supplements guide we wrote recently for more information.
Frequently Asked Questions about Racetams
Having any questions about this special group of brain supplements? We’ll try to answer some of those in the section below.
Are racetams illegal?
When it comes to matters legality, Racetams are to some extent a grey area. For something to qualify as safe for human consumption or to be legally sold in the market, it has to be a supplement, drug, or food.
For instance, in the U.S., the FDA has not sanctioned any of the racetams as a supplement or drug. That said, the government has not necessarily barred racetams either.
Therefore, while they are not illegal, there are no lawful restrictions for possession and consumption.
Are racetams addictive?
So, here is what you should keep in mind. By taking racetams, you alter your brain chemistry because you have introduced chemicals.
As such, you should consult your doctor before use. However, none of the racetams has been reported to initiate addictive behavior in either humans or animals.
You stand the risk of developing tolerance to racetams if you take them for an extended period. It is important to cycle your racetam intake every two months.
What are some of the side effects caused by racetams?
All the racetams exhibit more or less the same side effects, which may include;
This is not an exhaustive list of all the side effects you may experience when taking racetams. Consult with your physician about the side effects you may experience with a particular kind of racetam.
How do racetams work?
Racetams are reported to function by triggering glutamate receptors that are confined to cholinergic receptors.
This increases the regularity of stimulation of the latter.
Racetams are theorized to boost memory through communication with glutamate and cholinergic in the central nervous system.
What to stack racetams with?
You can never go wrong combining any type of racetam with a good source of choline such as Alpha GPC when looking for compounds to supplement your use of racetams.
In reality, the two compounds will have a synergistically affect each other.
This means that the effects of one or the other will be magnified to some extent.
Alpha GPC intensifies the creation of choline and this leads to an enhanced conversion of Acetylcholine and subsequently more potent and longer lasting racetam results.